NEW YORK (AP) -- A look at the 10 biggest volume gainers on Nasdaq at the close of trading:

Aerie Pharmaceuticals Inc. : Approximately 12,928,000 shares changed hands, a 2,961.1 percent increase over its 65-day average volume. The shares fell $22.52 or 63.6 percent to $12.87.

Catalyst Pharm : Approximately 13,212,400 shares changed hands, a 1,620.5 percent increase over its 65-day average volume. The shares fell $.98 or 21.0 percent to $3.69.

China Auto Logistics Inc. : Approximately 2,802,000 shares changed hands, a 3,189.1 percent increase over its 65-day average volume. The shares fell $.05 or 2.1 percent to $2.28.

DNB Financial Corp. : Approximately 14,600 shares changed hands, a 1,783.0 percent increase over its 65-day average volume. The shares rose $.62 or 2.5 percent to $25.62.

Guaranty Bancorp : Approximately 629,600 shares changed hands, a 2,835.7 percent increase over its 65-day average volume. The shares fell $1.12 or 6.6 percent to $15.74.

Lipocine Inc. : Approximately 1,341,200 shares changed hands, a 1,564.5 percent increase over its 65-day average volume. The shares fell $.27 or 3.8 percent to $6.85.

LookSmart Ltd. : Approximately 7,605,800 shares changed hands, a 4,897.7 percent increase over its 65-day average volume. The shares rose $.37 or 23.1 percent to $1.97.

Peoples Financial Corp. : Approximately 191,500 shares changed hands, a 2,223.9 percent increase over its 65-day average volume. The shares rose $.12 or 1.3 percent to $9.33.

Spectranetics Corp. : Approximately 6,564,100 shares changed hands, a 1,699.5 percent increase over its 65-day average volume. The shares fell $8.18 or 23.6 percent to $26.52.

stemCells Inc. : Approximately 21,433,900 shares changed hands, a 3,149.0 percent increase over its 65-day average volume. The shares fell $.21 or 25.6 percent to $.61.